particularly when mineral and fluid balance are affected.
Still, dry skin alone is much more likely to have another cause.
## 12. Muscle Cramps
Kidney problems can interfere with electrolyte balance, which may contribute to muscle cramping.
Possible factors include changes in:
* calcium
* phosphorus
* sodium
* potassium
Exercise, dehydration, and medications can cause cramps as well.
## 13. Restless Legs
Some people with chronic kidney disease experience uncomfortable sensations in the legs and an urge to move them, particularly at night.
This may be associated with restless legs syndrome, which can also occur