used alone as a sign of kidney disease.
## 16. Loss of Appetite
People with more advanced kidney disease may lose interest in food.
Possible reasons include:
* nausea
* altered taste
* general illness
* buildup of metabolic waste
Persistent appetite loss deserves medical evaluation.
## 17. Nausea or Vomiting
Severely reduced kidney function can lead to nausea and vomiting.
These symptoms are common in many other illnesses, so they are most concerning when combined with other signs such as swelling, major changes in urination, or severe weakness.
## 18. Unexplained Weight Loss
Weight loss without
